Auteur: yves
Date: 04-01-2006 09:43
Paru dans "Nature" du 24 novembre une technique photo faisant appel à des bactéries !!!!
Définition : 100 megapixel/pouce carré !!!
Principe simple : on met un gène (et tout ce qu'il y a derrière) exprimé sous l'influence de la lumière (il y en a dans toutes les plantes vertes, c'est la base de la photosynthèse) et on expose la culture bactérienne. Là où il y a eu de la lumière, production du pigment.
Si ça amuse quelqu'un de lire, j'ai le pdf à disposition.
Yves
"We have designed a bacterial system that is
switched between different states by red light.
The system consists of a synthetic sensor
kinase that allows a lawn of bacteria to function
as a biological film, such that the projection
of a pattern of light on to the bacteria
produces a high-definition (about 100 megapixels
per square inch), two-dimensional
chemical image. This spatial control of bacterial
gene expression could be used to ‘print’
complex biological materials, for example, and
to investigate signalling pathways through
precise spatial and temporal control of their
phosphorylation steps.
Plants and some bacteria use a class of protein
photoreceptors known as phytochromes
to control phototaxis, photosynthesis and the
production of protective pigments1–3. Photoreceptors
are not found in enterobacteria, such
as Escherichia coli, so we created a light sensor
that functions in E. coli by engineering a
chimaera that uses a phytochrome from a
cyanobacterium."
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